A 50th birthday is a milestone for most people and the speech should definitely signify this great achievement. Begin the speech by greeting all the guests present at the party and making a joke about how many birthdays the person has had already.

Include some of the attributes that the person has that make them special to you. If you have known the person for a long time, you can include some of the memories that you have about your past experiences together.

Include jokes about the physical activities that the person will find hard to do at age 50 in the speech. Joke about the person’s dreams about becoming a surfer or swimsuit model. This will definitely crack guests up at the party and make the person laugh at themselves.
If the person is a wife, husband, brother or sister, you can tell them about how much you value them and how they make your life better. You can mention some particular incidences where the person has been a great help to you.

At the end of the speech ask the guests to lift their glasses to celebrate the 50 years that the person has been in their lives.